U.S.-Supported Operations Against ISIS in Iraq and Syria
The campaign against ISIS, initiated in 2014 under Operation Inherent Resolve, aims to dismantle the group’s operational capabilities in Iraq and Syria.
MIDDLE EAST — From May 21 to May 27, 2025, U.S. Central Command supported partner forces in six operations targeting the Islamic State (ISIS) in Iraq and Syria, resulting in two ISIS operatives killed, two detained, including a senior leader, and the recovery of multiple weapons, according to USCENTCOM.
Historical Context
The campaign against ISIS, initiated in 2014 under Operation Inherent Resolve, aims to dismantle the group’s operational capabilities in Iraq and Syria.
The Combined Joint Task Force-Operation Inherent Resolve (CJTF-OIR), involving U.S. and multinational forces, has conducted sustained operations to prevent ISIS resurgence.
Video (May 6): U.S. Central Command: "U.S. Army Soldiers, part of the Coalition to defeat ISIS, conduct a live-fire exercise with an M119A3 Howitzer in the U.S. Central Command area of responsibility."
By 2019, ISIS lost its territorial caliphate, but remnants continue to pose threats through guerrilla tactics and sleeper cells, necessitating ongoing counter-terrorism efforts.
Acronym Index
USCENTCOM: U.S. Central Command
ISIS: Islamic State of Iraq and Syria
CJTF-OIR: Combined Joint Task Force-Operation Inherent Resolve
SDF: Syrian Democratic Forces
Timeline of Key Events
May 21–22, 2025: Syrian Democratic Forces, supported by USCENTCOM, conducted an operation near Deir ez-Zur, Syria, detaining one ISIS operative.
May 21–27, 2025: Iraqi forces, enabled by USCENTCOM, executed five operations in northern Iraq, including Salah al-Din, Kirkuk, and Al-Fallujah, resulting in two ISIS operatives killed, one ISIS leader detained, and the recovery of weapons and materials.
Total Reported Impact
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